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Myths about EBM

A recent article1 compiled a list of different myths that the medical community has believed and propagated.

1. "B12 can not be replenished orally in patients with pernicious anemia."

FALSE

Patients who received 500-1000 micrograms of oral B12 normalized their hemoglobin levels and had no neurologic sequelae in one 5-year study (Acta Med Scand 1968;184:247-58). Other studies confirmed this as well.

2. "Eye patches improve comfort and healing in corneal abrasions."

FALSE

Patients without eye patches did just as well or better (Opthalmology 1995;102:1936-42).

3. "Patients with diabetes should not use beta-blockers."

FALSE

There were no more instances of hypoglycemia that went unrecognized in those on or off beta-blockers (Br Med J 1980;280:976-8).

4. "Beta-blockers cause depression."

FALSE

In a cohort study, those who were on beta-blockers had just as much depression as those who were not on beta-blockers (J Clin Epidemiol 1996;49:809-15). It would be best if this question were evaluated in a randomized fashion, but that has yet to be done.

5. "Narcotics mask the signs in acute abdomen."

FALSE

A placebo controlled study demonstrated that surgeons were unable to tell which group had received narcotics, surgeons believed they had enough information in both groups, and outcomes were no different between the groups (BMJ 1992;305:554-6).

Key Point

A typical response might be: "Hold it! What is evidence-based medicine? I have been doing this (practicing medicine) for twenty years now. Why is what I do NOT evidence based medicine?"


1 Paauw DS. Did we learn evidence-based medicine in medical school? JABFP 1999;12(2):143-149.

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